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Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

for chest pain or use Rectogesic ointment?

• Nicorandil (Ikorel), used to treat angina

• Cimetidine, used to treat stomach or duodenal (peptic) ulcers

• Theophylline, used to treat asthma

• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

• Anti-fungals such as itraconazole and ketoconazole

• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

• Recreational drugs:- amyl nitrate (poppers)

If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

Read available consultation questionnaire information online and over the phone

The most common types of Tadalafil are used to treat erectile dysfunction (ED) and pulmonary arterial hypertension.

Tadalafil tablet

Tadalafil is the most commonly prescribed medication on the ED and PHA Medicine List. We also offer 24-hour alternatives to “intuitive” Tadalafil. In addition, we also provide generic Tadalafil alternatives such as Cialis, Levitra, and vardenafil. Notable generics of Tadalafil include :-

Cialis (tadalafil) is a EU Member State’s most used ED medication. Its generic (alprostadil nitrite) is also on the ED medication “intuitive” list.

Tadalafil 25mg

The generic (tadalafil) is also on the “intuitive” list, but it is more cost-effective than using the alventaren generic option. The generic (tadalafil) is more affordable and can be used as a regular option, or as a unique ED option.

Tadalafil 25mg single strength

Single-strength Tadalafil can cost more than twice the strength on theintuitive list. We only recommend generics of generic Tadalafil because of their superior quality and generic alternatives because of their affordable price.

Tadalafil 25mg daily

You can take Tadalafil 25mg daily if you are unable to take the strengths used for doxazosin and alvitrazosin to work well “intuitive.”

Tadalafil 25mg daily on most medications on the ED medication

Tadalafil on most medications on the “intuitive” list. However the alventaren option can make it more convenient.

Tadalafil on Rectogest

If you are taking a MAO inhibitor and have a doctor’s prescription, we will need your explicit permission before taking this medicine.

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The FDA has warned consumers not to purchase the Viagra drug from unlicensed online sites because the drug has the potential to cause serious side effects including vision loss, low blood pressure, heart problems and stroke. Read the FDA’s warning.

The FDA has warned consumers that the FDA has warned them not to purchase the medication because the drug has the potential to cause serious side effects including vision loss, low blood pressure, heart problems and stroke. The FDA has warned consumers that the FDA has warned them not to purchase the Viagra drug from unlicensed online sites because the drug has the potential to cause serious side effects including vision loss, low blood pressure, heart problems and stroke.

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The FDA has warned consumers that these websites may sell counterfeit drugs, which can be dangerous. Consumers should be aware of these websites, if they have one, and consult with their healthcare providers before using the drugs. Consumers with serious heart or blood vessel problems should use caution when using these sites, as the FDA has warned.

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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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